BACKGROUNDAlzheimer illness (AD) is a progressive dysfunction that impacts cognitive operate. There is growing assist for the function of neuroinflammation and aberrant immune regulation in the pathophysiology of AD. The immunoregulatory human leukocyte antigen (HLA) advanced has been linked to susceptibility for a quantity of neurodegenerative ailments, together with AD; nonetheless, research thus far have did not constantly determine a risk HLA haplotype for AD.
Contributing to this issue are the advanced genetic group of the HLA area, variations in sequencing and allelic imputation strategies, and variety throughout ethnic populations.RESULTSBuilding on prior work linking the HLA to AD, we used a sturdy imputation methodology on two separate case-control cohorts to look at the relationship between HLA haplotypes and AD risk in 309 people (191 AD, 118 cognitively regular [CN] controls) from the San Francisco-based University of California, San Francisco (UCSF) Memory and Aging Center (collected between 1999-2015) and 11,381 people (5,728 AD, 5,653 CN controls) from the Alzheimer’s Disease Genetics Consortium (ADGC), a National Institute on Aging (NIA)-funded nationwide information repository (reflecting samples collected between 1984-2012).
We additionally examined cerebrospinal fluid (CSF) biomarker measures for sufferers seen between 2005-2007 and longitudinal cognitive information from the Alzheimer’s Disease Neuroimaging Initiative (n = 346, imply follow-up 3.15 ± 2.04 y in AD people) to evaluate the medical relevance of recognized risk haplotypes. The strongest affiliation with AD risk occurred with main histocompatibility advanced (MHC) haplotype A*03:01~B*07:02~DRB1*15:01~DQA1*01:02~DQB1*06:02 (p = 9.6 x 10-4, odds ratio [OR] [95% confidence interval] = 1.21 [1.08-1.37]) in the mixed UCSF + ADGC cohort. Secondary evaluation prompt that this impact could also be pushed primarily by people who’re damaging for the established AD genetic risk factor, apolipoprotein E (APOE) É›4.
Separate analyses of class I and II haplotypes additional supported the function of class I haplotype A*03:01~B*07:02 (p = 0.03, OR = 1.11 [1.01-1.23]) and sophistication II haplotype DRB1*15:01- DQA1*01:02- DQB1*06:02 (DR15) (p = 0.03, OR = 1.08 [1.01-1.15]) as risk components for AD. We adopted up these findings in the medical dataset representing the spectrum of cognitively regular controls, people with delicate cognitive impairment, and people with AD to evaluate their relevance to illness.
Carrying A*03:01~B*07:02 was related to increased CSF amyloid ranges (p = 0.03, β ± commonplace error = 47.19 ± 21.78). We additionally discovered a dose-dependent affiliation between the DR15 haplotype and larger charges of cognitive decline (larger impairment on the 11-item Alzheimer’s Disease Assessment Scale cognitive subscale [ADAS11] over time [p = 0.03, β ± standard error = 0.7 ± 0.3]; worse forgetting rating on the Rey Auditory Verbal Learning Test (RAVLT) over time [p = 0.02, β ± standard error = -0.2 ± 0.06]). In a subset of the similar cohort, dose of DR15 was additionally related to increased baseline ranges of chemokine CC-4, a biomarker of irritation (p = 0.005, β ± commonplace error = 0.08 ± 0.03). The predominant research limitations are that the outcomes symbolize solely people of European-ancestry and clinically identified people, and that our research used imputed genotypes for a subset of HLA genes.
CONCLUSIONSWe present proof that variation in the HLA locus-including risk haplotype DR15-contributes to AD risk. DR15 has additionally been related to a number of sclerosis, and its part alleles have been implicated in Parkinson illness and narcolepsy. Our findings thus elevate the chance that DR15-associated mechanisms could contribute to pan-neuronal illness vulnerability.
Alpha-bungarotoxin, CF680r |
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| 9-00003 | Biotium |
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Description: Minimum order quantity: 1 unit of 100uG |
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Alpha-bungarotoxin, CF640r |
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| 9-00004 | Biotium |
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Description: Minimum order quantity: 1 unit of 500uG |
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Alpha-bungarotoxin, CF640r |
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| 9-00004 | Biotium |
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Description: Minimum order quantity: 1 unit of 100uG |
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Alpha-bungarotoxin, CF488a |
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| 9-00005 | Biotium |
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Description: Minimum order quantity: 1 unit of 500uG |
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Alpha-bungarotoxin CF488a |
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| 9-00005 | Biotium |
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Description: Minimum order quantity: 1 unit of 100uG |
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Alpha-bungarotoxin, CF568 |
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| 9-00006 | Biotium |
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Description: Minimum order quantity: 1 unit of 500uG |
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Alpha-bungarotoxin, CF568 |
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| 9-00006 | Biotium |
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Description: Minimum order quantity: 1 unit of 100uG |
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Alpha-bungarotoxin, CF594 |
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| 9-00007 | Biotium |
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Description: Minimum order quantity: 1 unit of 500uG |
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Alpha-bungarotoxin CF594 |
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| 9-00007 | Biotium |
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Description: Minimum order quantity: 1 unit of 100uG |
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Alpha-bungarotoxin, CF633 |
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| 9-00009 | Biotium |
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Description: Minimum order quantity: 1 unit of 500uG |
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Alpha-bungarotoxin, CF633 |
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| 9-00009 | Biotium |
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Description: Minimum order quantity: 1 unit of 100uG |
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Alpha-bungarotoxin |
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| 00010-1 | Biotium | 1MG | EUR 201.6 |
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Description: Minimum order quantity: 1 unit of 1MG |
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Fluorescein-Alpha-bungarotoxin |
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| 00011 | Biotium | 500uG | EUR 440.4 |
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Description: Minimum order quantity: 1 unit of 500uG |
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Tetramethylrhodamine-Alpha-bungarotoxin |
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| 00012 | Biotium | 500uG | EUR 459.6 |
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Description: Minimum order quantity: 1 unit of 500uG |
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Fluorescein-alpha-bungarotoxin: (10x50ug) |
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| 00013 | Biotium | 10ST | EUR 500.4 |
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Description: Minimum order quantity: 1 unit of 10ST |
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Tetramethylrhodamine-alpha-bungarotoxin: (10x50ug) |
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| 00014 | Biotium | 10ST | EUR 559.2 |
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Description: Minimum order quantity: 1 unit of 10ST |
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Sulforhodamine 101-a-bungarotoxin (Texas Red--a-bungarotoxin): (500ug) |
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| 00015 | Biotium | 500uG | EUR 559.2 |
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Description: Minimum order quantity: 1 unit of 500uG |
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Sulforhodamine 101-a-bungarotoxin (Texas Red--a-bungarotoxin): (10x50ug) |
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| 00016 | Biotium | 10ST | EUR 627.6 |
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Description: Minimum order quantity: 1 unit of 10ST |
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Biotin-xx-a-bungarotoxin |
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| 00017 | Biotium | 500uG | EUR 519.6 |
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Description: Minimum order quantity: 1 unit of 500uG |
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Alpha-Bungarotoxin, CF555 conjugate |
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| 9-00018 | Biotium |
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Description: Minimum order quantity: 1 unit of 500uG |
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Alpha-Bungarotoxin, CF555 conjugate |
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| 9-00018 | Biotium |
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Description: Minimum order quantity: 1 unit of 100ug |
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Biotin-cAMP, diisopropylethylammonium salt: |
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| 00020 | Biotium | 1MG | EUR 376.8 |
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Description: Minimum order quantity: 1 unit of 1MG |
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Biotin-cAMP, diisopropylethylammonium salt: (20x50ug) |
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| 00020-1 | Biotium | 20ST | EUR 501.6 |
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Description: Minimum order quantity: 1 unit of 20ST |
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Biotin-cGMP, diisopropylethylammonium salt: |
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| 00021 | Biotium | 1MG | EUR 412.8 |
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Description: Minimum order quantity: 1 unit of 1MG |
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Biotin-cGMP, diisopropylethylammonium salt: (20x50ug) |
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| 00021-1 | Biotium | 20ST | EUR 537.6 |
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Description: Minimum order quantity: 1 unit of 20ST |
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Cyanine 644-cAMP: |
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| 00022 | Biotium | 1MG | EUR 589.2 |
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Description: Minimum order quantity: 1 unit of 1MG |
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Cyanine 644-cAMP: (20x50ug) |
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| 00022-1 | Biotium | 20ST | EUR 750 |
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Description: Minimum order quantity: 1 unit of 20ST |
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Fluorescein Methotrexate, triammonium salt: |
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| 00023 | Biotium | 1MG | EUR 337.2 |
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Description: Minimum order quantity: 1 unit of 1MG |
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Staurosporine |
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| 00025 | Biotium | 100uG | EUR 166.8 |
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Description: Minimum order quantity: 1 unit of 100uG |
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Alpha-bungarotoxin, CF543 |
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| 00026 | Biotium | 500uG | EUR 592.8 |
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Description: Minimum order quantity: 1 unit of 500uG |
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Rhodamine phalloidin 300u |
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| 00027 | Biotium | 300 | EUR 414 |
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Description: Minimum order quantity: 1 unit of 300 |
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Biotin-xx-phalloidin |
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| 00028 | Biotium | 100U | EUR 513.6 |
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Description: Minimum order quantity: 1 unit of 100U |
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Fluorescein-phalloidin |
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| 00030 | Biotium | 300U | EUR 414 |
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Description: Minimum order quantity: 1 unit of 300U |
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Rhodamine 110 phalloidin |
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| 00032 | Biotium | 300ST | EUR 414 |
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Description: Minimum order quantity: 1 unit of 300ST |
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Sulforhodamine 101 (Texas-Red) Phalloidin |
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| 00033 | Biotium | 300EU | EUR 414 |
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Description: Minimum order quantity: 1 unit of 300EU |
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Phalloidin, CF405M |
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| 00034 | Biotium | 300U | EUR 530.4 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF405M |
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| 00034-T | Biotium | 50U | EUR 159.6 |
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Description: Minimum order quantity: 1 unit of 50U |
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CF488A-cAMP |
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| 00036 | Biotium | 100ug | EUR 206.4 |
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Description: Minimum order quantity: 1 unit of 100ug |
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CF640R-cAMP |
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| 00037 | Biotium | 100ug | EUR 206.4 |
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Description: Minimum order quantity: 1 unit of 100ug |
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Phalloidin, CF555 |
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| 00040 | Biotium | 300U | EUR 530.4 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF555 |
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| 00040-T | Biotium | 50U | EUR 159.6 |
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Description: Minimum order quantity: 1 unit of 50U |
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Phalloidin, CF647 |
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| 00041 | Biotium | 300U | EUR 530.4 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF647 |
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| 00041-T | Biotium | 50U | EUR 159.6 |
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Description: Minimum order quantity: 1 unit of 50U |
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Phalloidin, CF488A |
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| 00042 | Biotium | 300U | EUR 530.4 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF488A |
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| 00042-T | Biotium | 50U | EUR 159.6 |
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Description: Minimum order quantity: 1 unit of 50U |
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Phalloidin, CF543 |
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| 00043 | Biotium | 300U | EUR 530.4 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF543 |
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| 00043-T | Biotium | 50U | EUR 159.6 |
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Description: Minimum order quantity: 1 unit of 50U |
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Phalloidin, CF568 |
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| 00044 | Biotium | 300U | EUR 530.4 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF568 |
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| 00044-T | Biotium | 50U | EUR 159.6 |
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Description: Minimum order quantity: 1 unit of 50U |
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Phalloidin, CF594 |
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| 00045 | Biotium | 300U | EUR 530.4 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF594 |
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| 00045-T | Biotium | 50U | EUR 159.6 |
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Description: Minimum order quantity: 1 unit of 50U |
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Phalloidin, CF633 |
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| 00046 | Biotium | 300U | EUR 530.4 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF633 |
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| 00046-T | Biotium | 50U | EUR 159.6 |
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Description: Minimum order quantity: 1 unit of 50U |
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Phalloidin, CF660R |
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| 00047 | Biotium | 300U | EUR 530.4 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF660R |
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| 00047-T | Biotium | 50U | EUR 159.6 |
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Description: Minimum order quantity: 1 unit of 50U |
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Phalloidin, CF680R |
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| 00048 | Biotium | 300U | EUR 559.2 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF680R |
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| 00048-T | Biotium | 50U | EUR 159.6 |
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Description: Minimum order quantity: 1 unit of 50U |
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Phalloidin, CF350 |
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| 00049 | Biotium | 300U | EUR 530.4 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF350 |
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| 00049-T | Biotium | 50U | EUR 159.6 |
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Description: Minimum order quantity: 1 unit of 50U |
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Phalloidin, CF640R |
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| 00050 | Biotium | 300U | EUR 530.4 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF640R |
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| 00050-T | Biotium | 50U | EUR 159.6 |
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Description: Minimum order quantity: 1 unit of 50U |
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Phalloidin, CF532 |
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| 00051 | Biotium | 300U | EUR 530.4 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF532 |
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| 00051-T | Biotium | 50U | EUR 159.6 |
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Description: Minimum order quantity: 1 unit of 50U |
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Phalloidin, CF660C |
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| 00052 | Biotium | 300U | EUR 530.4 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF660C |
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| 00052-T | Biotium | 50U | EUR 159.6 |
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Description: Minimum order quantity: 1 unit of 50U |
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Phalloidin, CF680 |
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| 00053 | Biotium | 300U | EUR 559.2 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF680 |
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| 00053-T | Biotium | 50U | EUR 176.4 |
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Description: Minimum order quantity: 1 unit of 50U |
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Phalloidin, CF430 |
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| 00054 | Biotium | 300U | EUR 538.8 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF430 |
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| 00054-T | Biotium | 50U | EUR 166.8 |
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Description: Minimum order quantity: 1 unit of 50U |
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Phalloidin, CF440 |
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| 00055 | Biotium | 300U | EUR 538.8 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF440 |
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| 00055-T | Biotium | 50U | EUR 166.8 |
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Description: Minimum order quantity: 1 unit of 50U |
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Cholera Toxin Subunit B, CF488A conjugate |
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| 00070 | Biotium | 100ug | EUR 313.2 |
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Description: Minimum order quantity: 1 unit of 100ug |
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Cholera Toxin Subunit B, CF568 conjugate |
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| 00071 | Biotium | 100ug | EUR 313.2 |
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Description: Minimum order quantity: 1 unit of 100ug |
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Cholera Toxin Subunit B, CF594 conjugate |
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| 00072 | Biotium | 100ug | EUR 313.2 |
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Description: Minimum order quantity: 1 unit of 100ug |
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Cholera Toxin Subunit B, CF640R conjugate |
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| 00073 | Biotium | 100ug | EUR 316.8 |
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Description: Minimum order quantity: 1 unit of 100ug |
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Cholera Toxin Subunit B, CF532 conjugate |
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| 00074 | Biotium | 100ug | EUR 316.8 |
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Description: Minimum order quantity: 1 unit of 100ug |
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Cholera Toxin Subunit B, CF543 conjugate |
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| 00075 | Biotium | 100ug | EUR 316.8 |
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Description: Minimum order quantity: 1 unit of 100ug |
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Cholera Toxin Subunit B, CF620R conjugate |
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| 00076 | Biotium | 100ug | EUR 316.8 |
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Description: Minimum order quantity: 1 unit of 100ug |
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Cholera Toxin Subunit B, CF633 conjugate |
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| 00077 | Biotium | 100ug | EUR 316.8 |
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Description: Minimum order quantity: 1 unit of 100ug |
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Cholera Toxin Subunit B, CF660R conjugate |
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| 00078 | Biotium | 100ug | EUR 316.8 |
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Description: Minimum order quantity: 1 unit of 100ug |
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Cholera Toxin Subunit B, CF680R conjugate |
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| 00079 | Biotium | 100ug | EUR 338.4 |
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Description: Minimum order quantity: 1 unit of 100ug |
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Human Transferrin, CF488A conjugate |
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| 00081 | Biotium | 1mg | EUR 178.8 |
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Description: Minimum order quantity: 1 unit of 1mg |
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Human Transferrin, CF543 conjugate |
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| 00082 | Biotium | 1mg | EUR 178.8 |
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Description: Minimum order quantity: 1 unit of 1mg |
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Human Transferrin, CF568 conjugate |
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| 00083 | Biotium | 1mg | EUR 178.8 |
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Description: Minimum order quantity: 1 unit of 1mg |
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Human Transferrin, CF594 conjugate |
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| 00084 | Biotium | 1mg | EUR 178.8 |
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Description: Minimum order quantity: 1 unit of 1mg |
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Human Transferrin, CF640R conjugate |
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| 00085 | Biotium | 1mg | EUR 178.8 |
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Description: Minimum order quantity: 1 unit of 1mg |
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Human Transferrin, CF680R conjugate |
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| 00086 | Biotium | 1mg | EUR 178.8 |
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Description: Minimum order quantity: 1 unit of 1mg |
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Human Transferrin, CF750 conjugate |
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| 00087 | Biotium | 1mg | EUR 186 |
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Description: Minimum order quantity: 1 unit of 1mg |
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HIV-1 tat recombinant antigen |
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| 00110-V-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HIV-1 tat recombinant antigen full length 15 kDa |
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HIV-1 tat recombinant antigen |
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| 00110-V-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HIV-1 tat recombinant antigen full length 15 kDa |
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HIV-1 GAG P24 Recombinant Antigen |
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| 00111-V-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HIV-1 gag p24 recombinant antigen a.a 77 to a.a 436 of the HIV-1 gag region 39 kDa |
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HIV-1 GAG P24 Recombinant Antigen |
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| 00111-V-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HIV-1 gag p24 recombinant antigen a.a 77 to a.a 436 of the HIV-1 gag region 39 kDa |
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HIV-1 nef recombinant antigen |
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| 00112-V-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HIV-1 nef recombinant antigen a.a 3 to a.a 190 of the HIV-1 nef region 20 kDa |
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HIV-1 nef recombinant antigen |
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| 00112-V-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HIV-1 nef recombinant antigen a.a 3 to a.a 190 of the HIV-1 nef region 20 kDa |
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HIV-1 env gp41 recombinant antigen |
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| 00113-V-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HIV-1 env gp41 recombinant antigen a.a 466 to a.a 753 of the HIV-1 env region 32 kDa |
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HIV-1 env gp41 recombinant antigen |
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| 00113-V-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HIV-1 env gp41 recombinant antigen a.a 466 to a.a 753 of the HIV-1 env region 32 kDa |
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HIV-2 GP 36 Recombinant Antigen |
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| 00114-V-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HIV -2 env gp36 recombinant antigen a.a 390 to a.a 702 of the HIV-2 env region 34 kDa |
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HIV-2 GP 36 Recombinant Antigen |
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| 00114-V-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HIV -2 env gp36 recombinant antigen a.a 390 to a.a 702 of the HIV-2 env region 34 kDa |
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HCV core recombinant antigen |
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| 00115-V-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa |
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HCV core recombinant antigen |
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| 00115-V-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa |
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HCV core recombinant antigen, Biotin conjugate |
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| 00115-V-B-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa. Biotin conjugate. |
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HCV core recombinant antigen, Biotin conjugate |
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| 00115-V-B-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa. Biotin conjugate. |
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HCV core recombinant antigen, FITC conjugate |
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| 00115-V-F-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa. Fluorescein conjugate. |
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HCV core recombinant antigen, FITC conjugate |
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| 00115-V-F-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa. Fluorescein conjugate. |
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HCV core recombinant antigen, Rhodamine |
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| 00115-V-R-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa . Rhodamine conjugate. |
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HCV core recombinant antigen, Rhodamine |
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| 00115-V-R-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa . Rhodamine conjugate. |
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HCV NS4 recombinant antigen NS4a+b |
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| 00116-V-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. |
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HCV NS4 recombinant antigen NS4a+b |
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| 00116-V-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. |
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HCV NS4 recombinant antigen NS4a+b, Biotin |
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| 00116-V-B-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Biotin conjugate. |
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HCV NS4 recombinant antigen NS4a+b, Biotin |
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| 00116-V-B-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Biotin conjugate. |
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HCV NS4 recombinant antigen NS4a+b, FITC |
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| 00116-V-F-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Fluorescein conjugate. |
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HCV NS4 recombinant antigen NS4a+b, FITC |
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| 00116-V-F-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Fluorescein conjugate. |
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HCV NS4 recombinant antigen NS4a+b, Rhodamine |
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| 00116-V-R-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Rhodamine conjugate. |
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HCV NS4 recombinant antigen NS4a+b, Rhodamine |
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| 00116-V-R-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Rhodamine conjugate. |
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HCV NS3 recombinant antigen |
|||
| 00117-V-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HCV NS3 recombinant antigen a.a 1400 to a.a 1643 of HCV polyprotein 22 kDa |
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HCV NS3 recombinant antigen |
|||
| 00117-V-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HCV NS3 recombinant antigen a.a 1400 to a.a 1643 of HCV polyprotein 22 kDa |
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HBV core recombinant antigen |
|||
| 00120-V-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HBV core recombinant antigen HBcAg a.a 1 to a.a 183 of HBV core antigen 18 kDa |
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HBV core recombinant antigen |
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| 00120-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HBV core recombinant antigen HBcAg a.a 1 to a.a 183 of HBV core antigen 18 kDa |
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HBV core recombinant antigen, Delta |
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| 00121-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: HBV core recombinant antigen HBcAg a.a 1 to a.a 144 of HBV core antigen 16 kDa |
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HBV core recombinant antigen, Delta |
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| 00121-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HBV core recombinant antigen HBcAg a.a 1 to a.a 144 of HBV core antigen 16 kDa |
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HBV surface recombinant antigen HBsAg |
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| 00122-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant |
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HBV surface recombinant antigen HBsAg |
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| 00122-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant |
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HBV surface recombinant antigen HBsAg antigen |
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| 00123-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant High purity |
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HBV surface recombinant antigen HBsAg antigen |
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| 00123-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant High purity |
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HBV surface recombinant antigen HBsAg antigen |
|||
| 00124-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: HBV surface recombinant antigen HBsAg antigen 31 kDa E. coli recombinant |
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HBV surface recombinant antigen HBsAg antigen |
|||
| 00124-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HBV surface recombinant antigen HBsAg antigen 31 kDa E. coli recombinant |
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HEV (Birma) ORF2 recombinant antigen |
|||
| 00131-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: HEV (Birma) ORF2 recombinant antigen a.a. 633 to a.a 659. |
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HEV (Birma) ORF2 recombinant antigen |
|||
| 00131-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HEV (Birma) ORF2 recombinant antigen a.a. 633 to a.a 659. |
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HEV (Birma) ORF2 recombinant antigen |
|||
| 00132-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: HEV (Birma) ORF2 recombinant antigen a.a. 403 to a.a 461. |
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HEV (Birma) ORF2 recombinant antigen |
|||
| 00132-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HEV (Birma) ORF2 recombinant antigen a.a. 403 to a.a 461. |
|||
AA 403-461 HEV Birma ORF2 Recombinant Antigen |
|||
| 00133-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: HEV (Birma) ORF2 recombinant antigen a.a. 92 to a.a 123. |
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AA 403-461 HEV Birma ORF2 Recombinant Antigen |
|||
| 00133-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HEV (Birma) ORF2 recombinant antigen a.a. 92 to a.a 123. |
|||
T, Pallidum recombinant antigen p15 |
|||
| 00141-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: T. Pallidum recombinant antigen p15 (full length) |
|||
T, Pallidum recombinant antigen p15 |
|||
| 00141-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: T. Pallidum recombinant antigen p15 (full length) |
|||
T, Pallidum recombinant antigen p17 |
|||
| 00142-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: T. Pallidum recombinant antigen p17 (full length) |
|||
T, Pallidum recombinant antigen p17 |
|||
| 00142-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: T. Pallidum recombinant antigen p17 (full length) |
|||
T, Pallidum recombinant antigen p45 |
|||
| 00143-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: T. Pallidum recombinant antigen p45 (full length) |
|||
T, Pallidum recombinant antigen p45 |
|||
| 00143-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: T. Pallidum recombinant antigen p45 (full length) |
|||
T, pallidum recombinant antigen TmpA |
|||
| 00144-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: T. Pallidum recombinant antigen TmpA (full length) |
|||
T, pallidum recombinant antigen TmpA |
|||
| 00144-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: T. Pallidum recombinant antigen TmpA (full length) |
|||
HCV core 2-119aa recombinant antigen |
|||
| 00150-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: HCV core 2-119aa recombinant antigen. Genotypes available: 1a, 1b, 2a, 2b, 3a, 3b, 3/10, 4, 5, 6a |
|||
HCV core 2-119aa recombinant antigen |
|||
| 00150-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HCV core 2-119aa recombinant antigen. Genotypes available: 1a, 1b, 2a, 2b, 3a, 3b, 3/10, 4, 5, 6a |
|||
HCV Core 24 Antigen |
|||
| 00151-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: HCV core 24 antigen. |
|||
HCV Core 24 Antigen |
|||
| 00151-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HCV core 24 antigen. |
|||
HCV core recombinant antigen |
|||
| 00152-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: HCV core recombinant antigen a.a.105-302 |
|||
HCV core recombinant antigen |
|||
| 00152-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HCV core recombinant antigen a.a.105-302 |
|||
HCV NS3 1192-1456 aa Recombinant Antigen |
|||
| 00153-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: HCV NS3 1192-1456aa recombinant antigen a.a.1192-1459. Available genotypes: 1a, 1b, 2b, 2c, 5, 6a |
|||
HCV NS3 1192-1456 aa Recombinant Antigen |
|||
| 00153-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HCV NS3 1192-1456aa recombinant antigen a.a.1192-1459. Available genotypes: 1a, 1b, 2b, 2c, 5, 6a |
|||
HCV NS3 1359-1456aa antigen |
|||
| 00154-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: HCV NS3 1359-1456aa antigen. The protein contains immunodominant regions (1359-1456aa). available genotypes: 1a, 1b, 2b, 3, 4, 5, 6 |
|||
HCV NS3 1359-1456aa antigen |
|||
| 00154-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HCV NS3 1359-1456aa antigen. The protein contains immunodominant regions (1359-1456aa). available genotypes: 1a, 1b, 2b, 3, 4, 5, 6 |
|||
HCV NS4 mosaic recombinant antigen |
|||
| 00155-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: HCV NS4 mosaic recombinant antigen a.a1691-1710, 1712-1733, 1921-1940. Genotypes available: 1, 2, 3, 5. |
|||
HCV NS4 mosaic recombinant antigen |
|||
| 00155-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HCV NS4 mosaic recombinant antigen a.a1691-1710, 1712-1733, 1921-1940. Genotypes available: 1, 2, 3, 5. |
|||
HCV NS4 1916-1947aa recombinant antigen |
|||
| 00156-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: HCV NS4 1916-1947aa recombinant antigen. |
|||
HCV NS4 1916-1947aa recombinant antigen |
|||
| 00156-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HCV NS4 1916-1947aa recombinant antigen. |
|||
HCV NS5 2061-2302aa recombinant antigen |
|||
| 00157-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: HCV NS5 2061-2302aa recombinant antigen. |
|||
HCV NS5 2061-2302aa recombinant antigen |
|||
| 00157-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HCV NS5 2061-2302aa recombinant antigen. |
|||
HCV NS5 2212-2313aa recombinant antigen |
|||
| 00158-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: HCV NS5 2212-2313aa recombinant antigen. Available genotypes: 1a, 1b, 2a, 2b, 3a, 3b, 4, 5, 6a. |
|||
HCV NS5 2212-2313aa recombinant antigen |
|||
| 00158-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HCV NS5 2212-2313aa recombinant antigen. Available genotypes: 1a, 1b, 2a, 2b, 3a, 3b, 4, 5, 6a. |
|||
HAV VP1-P2A recombinant antigen |
|||
| 00159-V-01mg | Virogen | 0,1 mg | EUR 321 |
|
Description: HAV VP1-P2A recombinant antigen a.a. 722-830. |
|||
HAV VP1-P2A recombinant antigen |
|||
| 00159-V-1000ug | Virogen | 1000 ug | EUR 1539 |
|
Description: HAV VP1-P2A recombinant antigen a.a. 722-830. |
|||