Do Cerebral Small Vessel Disease and Multiple Sclerosis Share Common Mechanisms of White Matter Injury?

Do Cerebral Small Vessel Disease and Multiple Sclerosis Share Common Mechanisms of White Matter Injury?

Background and Purpose- The function of irritation in ischemic white matter illness is more and more acknowledged, and additional understanding of the pathophysiology may inform future remedy methods. Multiple sclerosis (MS) is a continual autoimmune situation wherein irritation performs a central function that additionally impacts the white matter.

We hypothesized that white matter damage may share widespread mechanisms and used statistical genetics methods to evaluate whether or not having genetically elevated white matter hyperintensity (WMH) quantity was related to elevated MS threat. Methods- We investigated the genetic affiliation in 2 cohorts with magnetic resonance imaging-quantified ischemic white matter lesion quantity (WMH in stroke; n=2797 and UK Biobank; n=8353) and 14 802 circumstances of MS and 26 703 controls from the International Multiple Sclerosis Genetics Consortium.

We additional carried out individual-level polygenic threat rating calculations for MS and measures of structural white matter illness in UK Biobank. Finally, we seemed for proof of overlapping threat throughout the entire genome. Results- There was no affiliation of genetic variants influencing MS with WMH quantity utilizing abstract statistics within the WMH in stroke cohort (relative threat rating =1.014; 95% CI, 0.936-1.110) or within the UK Biobank cohort (relative threat rating =1.030; 95% CI, 0.932-1.117). Conversely, assessing the contribution of single nucleotide polymorphisms considerably related to WMH on the danger of MS there was no important affiliation (relative threat rating =0.930; 95% CI, 0.736-1.191).

Do Cerebral Small Vessel Disease and Multiple Sclerosis Share Common Mechanisms of White Matter Injury?
Do Cerebral Small Vessel Disease and Multiple Sclerosis Share Common Mechanisms of White Matter Injury?

There have been no important associations between polygenic threat scores calculations; these outcomes have been strong to the choice of single nucleotide polymorphisms at a spread of significance thresholds. Whole genome evaluation didn’t reveal any overlap of threat between the traits. Conclusions- Our outcomes don’t present proof to counsel a shared mechanism of white matter harm in ischemia and MS. We suggest that irritation acts in distinct pathways as a result of of the differing nature of the first insult.

General Dihydrotestosterone (DHT) ELISA Kit

RDR-DHT-Ge-48Tests 48 Tests
EUR 585.6

General Dihydrotestosterone (DHT) ELISA Kit

RDR-DHT-Ge-96Tests 96 Tests
EUR 811.2

DHT Antibody

20R-DR011W 1000 tests
EUR 159.6
Description: Rabbit polyclonal DHT antibody

Dihydrotestosterone(DHT)

B8214-100 100 mg
EUR 369.6

Dihydrotestosterone(DHT)

B8214-25 25 mg
EUR 189.6

Dihydrotestosterone (DHT) Antibody

10291-05011 150 ug
EUR 260.4

Dihydrotestosterone (DHT) Antibody

10301-05011 150 ug
EUR 260.4

Dihydrotestosterone (DHT) Antibody

20-abx101749
  • EUR 343.20
  • EUR 159.60
  • EUR 878.40
  • EUR 477.60
  • EUR 309.60
  • 100 ug
  • 10 ug
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  • 200 ug
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Dihydrotestosterone (DHT) ELISA Kit

20-abx150335
  • EUR 9004.80
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  • 10 × 96 tests
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Dihydrotestosterone (DHT) Antibody (Biotin)

20-abx274269
  • EUR 493.20
  • EUR 276.00
  • EUR 1395.60
  • EUR 678.00
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  • 100 ug
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  • 200 ug
  • 50 ug

Dihydrotestosterone (DHT) ELISA Kit

abx575390-96tests 96 tests
EUR 801.6

Dihydrotestosterone (DHT) ELISA Kit

abx257148-96tests 96 tests
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Dihydrotestosterone (DHT) CLIA Kit

20-abx490107
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Dihydrotestosterone (DHT) CLIA Kit

abx195018-96tests 96 tests
EUR 990

BSA Conjugated Dihydrotestosterone (DHT)

4-CPA443Ge11
  • EUR 496.32
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  • EUR 590.40
  • EUR 1060.80
  • EUR 408.00
  • EUR 3648.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
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Description: Recombinant Pan-species Dihydrotestosterone expressed in: Protein conjugation

OVA Conjugated Dihydrotestosterone (DHT)

4-CPA443Ge21
  • EUR 496.32
  • EUR 256.80
  • EUR 1531.20
  • EUR 590.40
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  • EUR 408.00
  • EUR 3648.00
  • 100 ug
  • 10ug
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  • 200 ug
  • 500 ug
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Description: Recombinant Pan-species Dihydrotestosterone expressed in: Protein conjugation

Porcine DHT ELISA Kit

EPD0008 96Tests
EUR 625.2

Rabbit DHT ELISA Kit

ERTD0008 96Tests
EUR 625.2

Rat DHT ELISA Kit

ERD0008 96Tests
EUR 625.2

Mouse DHT ELISA Kit

EMD0008 96Tests
EUR 625.2

Monkey DHT ELISA Kit

EMKD0008 96Tests
EUR 625.2

Human DHT ELISA Kit

EHD0008 96Tests
EUR 625.2

Goat DHT ELISA Kit

EGTD0008 96Tests
EUR 625.2

Dihydrotestosterone (DHT) ELISA Kit

E4604-100
EUR 874.8

Canine DHT ELISA Kit

ECD0008 96Tests
EUR 625.2

Chicken DHT ELISA Kit

ECKD0008 96Tests
EUR 625.2

Anserini DHT ELISA Kit

EAD0008 96Tests
EUR 625.2

Bovine DHT ELISA Kit

EBD0008 96Tests
EUR 625.2

DHT(Dihydrotestosterone) ELISA Kit

EU2551 96T
EUR 571.5
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: General;Sensitivity: 23.438pg/ml

Sheep DHT ELISA Kit

ESD0008 96Tests
EUR 625.2

Bromperidol (powder)

50R-R11333 50 mg
EUR 159.6
Description: Bromperidol chemical reference substance

Flubendazole (powder)

50R-R17890 50 mg
EUR 216
Description: Flubendazole chemical reference substance

Flunarizine (powder)

50R-R18545 50 mg
EUR 159.6
Description: Flunarizine chemical reference substance

Azaperone (powder)

50R-R1929 50 mg
EUR 159.6
Description: Azaperone chemical reference substance

Closantel (powder)

50R-R23050 50 mg
EUR 216
Description: Closantel chemical reference substance

Enilconazole (powder)

50R-R30617 50 mg
EUR 216
Description: Enilconazole chemical reference substance

Ketoconazole (powder)

50R-R41400 50 mg
EUR 159.6
Description: Ketoconazole chemical reference substance

Cisapride (powder)

50R-R51619 50 mg
EUR 159.6
Description: Cisapride chemical reference substance

Diclazuril (powder)

50R-R62370 50 mg
EUR 289.2
Description: Diclazuril chemical reference substance

Diclazuril (powder)

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EUR 289.2
Description: Diclazuril chemical reference substance

Albuterol (powder)

51R-U012600 200 mg
EUR 619.2
Description: Albuterol chemical reference substance

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97R-1001 10 mg
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Description: Purified Risperidone powder

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97R-1003 100 mg
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Description: Diclazuril chemical reference substance

Puromycin,Powder

CR028-001 100mg
EUR 230.4

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CR028-005 500mg
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CR028-101 1g
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HEMOGLOBIN POWDER

H08-103-10kg 10 kg
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Description: Polyvinylpyrrolidone (PVPP) used for preparation of wine samples for use with the QuantiQuikâ„¢ Histamine Quick Test Strips .

Human Dihydrotestosterone,DHT ELISA Kit

201-12-1066 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

General Dihydrotestosterone (DHT) ELISA Kit

CEA443Ge-10x96wellstestplate 10x96-wells test plate
EUR 6431.78
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Dihydrotestosterone (DHT) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Dihydrotestosterone (DHT) ELISA Kit

CEA443Ge-1x48wellstestplate 1x48-wells test plate
EUR 634.85
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Dihydrotestosterone (DHT) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Dihydrotestosterone (DHT) ELISA Kit

CEA443Ge-1x96wellstestplate 1x96-wells test plate
EUR 855.5
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Dihydrotestosterone (DHT) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Dihydrotestosterone (DHT) ELISA Kit

CEA443Ge-5x96wellstestplate 5x96-wells test plate
EUR 3489.77
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Dihydrotestosterone (DHT) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Dihydrotestosterone (DHT) ELISA Kit

4-CEA443Ge
  • EUR 6492.00
  • EUR 3430.80
  • EUR 855.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of General Dihydrotestosterone (DHT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Canine Dihydrotestosterone,DHT ELISA Kit

CN-00948C1 96T
EUR 558

Canine Dihydrotestosterone,DHT ELISA Kit

CN-00948C2 48T
EUR 378

Human Dihydrotestosterone, DHT ELISA Kit

CSB-E07878h-24T 1 plate of 24 wells
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Description: Quantitativecompetitive ELISA kit for measuring Human Dihydrotestosterone, DHT in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Dihydrotestosterone, DHT ELISA Kit

1-CSB-E07878h
  • EUR 1080.00
  • EUR 6571.20
  • EUR 3480.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Human Dihydrotestosterone, DHT in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Dihydrotestosterone, DHT ELISA Kit

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EUR 198
Description: Quantitativecompetitive ELISA kit for measuring Rat Dihydrotestosterone, DHT in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Dihydrotestosterone, DHT ELISA Kit

1-CSB-E07879r
  • EUR 1160.40
  • EUR 7110.00
  • EUR 3760.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Rat Dihydrotestosterone, DHT in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Dihydrotestosterone, DHT ELISA Kit

CSB-E07880m-24T 1 plate of 24 wells
EUR 198
Description: Quantitativecompetitive ELISA kit for measuring Mouse Dihydrotestosterone, DHT in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Dihydrotestosterone, DHT ELISA Kit

1-CSB-E07880m
  • EUR 1135.20
  • EUR 6938.40
  • EUR 3672.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Mouse Dihydrotestosterone, DHT in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Canine Dihydrotestosterone, DHT ELISA Kit

CSB-E07881c-24T 1 plate of 24 wells
EUR 198
Description: Quantitativecompetitive ELISA kit for measuring Canine Dihydrotestosterone, DHT in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Canine Dihydrotestosterone, DHT ELISA Kit

1-CSB-E07881c
  • EUR 1160.40
  • EUR 7110.00
  • EUR 3760.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Canine Dihydrotestosterone, DHT in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Bovine Dihydrotestosterone, DHT ELISA Kit

CELI-66100b 96 Tests
EUR 1113.6

Chicken Dihydrotestosterone, DHT ELISA Kit

CELI-66100c 96 Tests
EUR 1113.6

Canine Dihydrotestosterone, DHT ELISA Kit

CELI-66100d 96 Tests
EUR 1113.6

General Dihydrotestosterone, DHT ELISA Kit

CELI-66100Ge 96 Tests
EUR 1063.2

Human Dihydrotestosterone, DHT ELISA Kit

CELI-66100h 96 Tests
EUR 988.8

Mouse Dihydrotestosterone, DHT ELISA Kit

CELI-66100m 96 Tests
EUR 1038

Porcine Dihydrotestosterone, DHT ELISA Kit

CELI-66100p 96 Tests
EUR 1113.6

Rat Dihydrotestosterone, DHT ELISA Kit

CELI-66100r 96 Tests
EUR 1063.2

Rabbit Dihydrotestosterone, DHT ELISA Kit

CELI-66100Rb 96 Tests
EUR 1113.6

Mouse Dihydrotestosterone,DHT ELISA Kit

CN-02814M1 96T
EUR 529.2

Mouse Dihydrotestosterone,DHT ELISA Kit

CN-02814M2 48T
EUR 349.2

Human Dihydrotestosterone,DHT ELISA Kit

CN-03926H1 96T
EUR 537.6

Human Dihydrotestosterone,DHT ELISA Kit

CN-03926H2 48T
EUR 356.4

Rat Dihydrotestosterone,DHT ELISA Kit

CN-01938R1 96T
EUR 576

Rat Dihydrotestosterone,DHT ELISA Kit

CN-01938R2 48T
EUR 397.2

ELISA kit for DHT (Dihydrotestosterone)

E-EL-0031 1 plate of 96 wells
EUR 452.4
Description: A competitive ELISA kit for quantitative measurement of DHT (Dihydrotestosterone) in samples from Serum, Plasma, Cell supernatant

General DHT/ Dihydrotestosterone ELISA Kit

E0026Ge 1 Kit
EUR 860.4

Guinea Pig DHT ELISA Kit

EGD0008 96Tests
EUR 625.2

Chicken DHT(Dihydrotestosterone) ELISA Kit

ECH0114 96T
EUR 681.12
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Chicken;Sensitivity: 22.5pg/ml

Dihydrotestosterone (DHT) AssayMax ELISA Kit

ED3010-1 96 Well Plate
EUR 500.4

Human Dihydrotestosterone(DHT)ELISA Kit

GA-E1082HM-48T 48T
EUR 346.8

Human Dihydrotestosterone(DHT)ELISA Kit

GA-E1082HM-96T 96T
EUR 559.2

Rat Dihydrotestosterone(DHT)ELISA Kit

GA-E0571RT-48T 48T
EUR 380.4

Rat Dihydrotestosterone(DHT)ELISA Kit

GA-E0571RT-96T 96T
EUR 595.2

Mouse Dihydrotestosterone(DHT)ELISA Kit

GA-E0700MS-48T 48T
EUR 403.2

Mouse Dihydrotestosterone(DHT)ELISA Kit

GA-E0700MS-96T 96T
EUR 640.8

Dihydrotestosterone (DHT) Polyclonal Antibody (General)

4-PAA443Ge01
  • EUR 273.60
  • EUR 2662.80
  • EUR 670.80
  • EUR 339.60
  • EUR 247.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against General Dihydrotestosterone (DHT)

General Dihydrotestosterone ELISA Kit (DHT)

RK00648 96 Tests
EUR 625.2

Human Dihydrotestosterone(DHT)ELISA Kit

QY-E01470 96T
EUR 433.2

Rat Dihydrotestosterone(DHT)ELISA Kit

QY-E11081 96T
EUR 433.2

Mouse Dihydrotestosterone(DHT)ELISA Kit

QY-E20472 96T
EUR 433.2

Canine Dihydrotestosterone,DHT ELISA Kit

QY-E70040 96T
EUR 511.2

Canine Dihydrotestosterone,DHT ELISA Kit

QY-E70126 96T
EUR 511.2

Econazole Nitrate (powder)

50R-R14827 50 mg
EUR 159.6
Description: Econazole Nitrate chemical reference substance

Levocabastine HCL (powder)

50R-R50547 50 mg
EUR 159.6
Description: Levocabastine HCL chemical reference substance

Clocinizine HCL (powder)

50R-R522 50 mg
EUR 159.6
Description: Clocinizine HCL chemical reference substance

Nor Astemizole (powder)

50R-R53993 50 mg
EUR 289.2
Description: Nor Astemizole chemical reference substance

Hydroxy-itraconazole (powder)

50R-R63373 50 mg
EUR 289.2
Description: Hydroxy-itraconazole chemical reference substance

Levamisole OMPI (powder)

50R-R9280 50 mg
EUR 159.6
Description: Levamisole OMPI chemical reference substance

Acetylcholine Chloride (powder)

51R-U008501 200 mg
EUR 619.2
Description: Acetylcholine Chloride chemical reference substance

Colistin Sulfate (powder)

51R-U148001 200 mg
EUR 619.2
Description: Colistin Sulfate chemical reference substance

Congo Red Powder

abx090680-5g 5 g
EUR 226.8

Hemoglobin Powder (bovine)

97R-1004S 1 Kg
EUR 1318.8

Bevacizumab Lyophilized powder

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Citrate Buffer Powder

AR0024 2000mL/pack
EUR 63.6

Beef Extract Powder

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EUR 152.4

Beef Extract Powder

CH017 100 g
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Beef Extract Powder

CH018 500 g
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Soya lecithin, powder

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Soya lecithin, powder

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Soya lecithin, powder

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