Do Cerebral Small Vessel Disease and Multiple Sclerosis Share Common Mechanisms of White Matter Injury?

Do Cerebral Small Vessel Disease and Multiple Sclerosis Share Common Mechanisms of White Matter Injury?

Background and Purpose- The function of irritation in ischemic white matter illness is more and more acknowledged, and additional understanding of the pathophysiology may inform future remedy methods. Multiple sclerosis (MS) is a continual autoimmune situation wherein irritation performs a central function that additionally impacts the white matter.

We hypothesized that white matter damage may share widespread mechanisms and used statistical genetics methods to evaluate whether or not having genetically elevated white matter hyperintensity (WMH) quantity was related to elevated MS threat. Methods- We investigated the genetic affiliation in 2 cohorts with magnetic resonance imaging-quantified ischemic white matter lesion quantity (WMH in stroke; n=2797 and UK Biobank; n=8353) and 14 802 circumstances of MS and 26 703 controls from the International Multiple Sclerosis Genetics Consortium.

We additional carried out individual-level polygenic threat rating calculations for MS and measures of structural white matter illness in UK Biobank. Finally, we seemed for proof of overlapping threat throughout the entire genome. Results- There was no affiliation of genetic variants influencing MS with WMH quantity utilizing abstract statistics within the WMH in stroke cohort (relative threat rating =1.014; 95% CI, 0.936-1.110) or within the UK Biobank cohort (relative threat rating =1.030; 95% CI, 0.932-1.117). Conversely, assessing the contribution of single nucleotide polymorphisms considerably related to WMH on the danger of MS there was no important affiliation (relative threat rating =0.930; 95% CI, 0.736-1.191).

Do Cerebral Small Vessel Disease and Multiple Sclerosis Share Common Mechanisms of White Matter Injury?
Do Cerebral Small Vessel Disease and Multiple Sclerosis Share Common Mechanisms of White Matter Injury?

There have been no important associations between polygenic threat scores calculations; these outcomes have been strong to the choice of single nucleotide polymorphisms at a spread of significance thresholds. Whole genome evaluation didn’t reveal any overlap of threat between the traits. Conclusions- Our outcomes don’t present proof to counsel a shared mechanism of white matter harm in ischemia and MS. We suggest that irritation acts in distinct pathways as a result of of the differing nature of the first insult.

General Dihydrotestosterone (DHT) ELISA Kit

RDR-DHT-Ge-48Tests 48 Tests
EUR 488.00

General Dihydrotestosterone (DHT) ELISA Kit

RDR-DHT-Ge-96Tests 96 Tests
EUR 676.00

General Dihydrotestosterone (DHT) ELISA Kit

RD-DHT-Ge-48Tests 48 Tests
EUR 467.00

General Dihydrotestosterone (DHT) ELISA Kit

RD-DHT-Ge-96Tests 96 Tests
EUR 646.00

Dihydrotestosterone(DHT)

B8214-100 100 mg
EUR 308.00

Dihydrotestosterone(DHT)

B8214-25 25 mg
EUR 158.00

DHT Antibody

20R-DR011W 1000 tests
EUR 133.00
Description: Rabbit polyclonal DHT antibody

Dihydrotestosterone (DHT) Antibody

20-abx101749
  • EUR 286.00
  • EUR 133.00
  • EUR 732.00
  • EUR 398.00
  • EUR 258.00
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  • Shipped within 5-7 working days.

Dihydrotestosterone (DHT) Antibody

10291-05011 150 ug
EUR 217.00

Dihydrotestosterone (DHT) Antibody

10301-05011 150 ug
EUR 217.00

Dihydrotestosterone (DHT) ELISA Kit

abx575390-96tests 96 tests
EUR 668.00
  • Shipped within 5-12 working days.

Human DHT ELISA Kit

EHD0008 96Tests
EUR 521.00

Goat DHT ELISA Kit

EGTD0008 96Tests
EUR 521.00

Canine DHT ELISA Kit

ECD0008 96Tests
EUR 521.00

Chicken DHT ELISA Kit

ECKD0008 96Tests
EUR 521.00

Dihydrotestosterone (DHT) ELISA Kit

E4604-100
EUR 729.00

Bovine DHT ELISA Kit

EBD0008 96Tests
EUR 521.00

Anserini DHT ELISA Kit

EAD0008 96Tests
EUR 521.00

Porcine DHT ELISA Kit

EPD0008 96Tests
EUR 521.00

Rat DHT ELISA Kit

ERD0008 96Tests
EUR 521.00

Rabbit DHT ELISA Kit

ERTD0008 96Tests
EUR 521.00

Sheep DHT ELISA Kit

ESD0008 96Tests
EUR 521.00

DHT(Dihydrotestosterone) ELISA Kit

EU2551 96T
EUR 476.25
  • Detection range: 39.063-2500 pg/ml
  • Alias: DHT(Dihydrotestosterone)
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: General;Sensitivity: 23.438pg/ml

Mouse DHT ELISA Kit

EMD0008 96Tests
EUR 521.00

Monkey DHT ELISA Kit

EMKD0008 96Tests
EUR 521.00

Dihydrotestosterone (DHT) ELISA Kit

20-abx150335
  • EUR 7504.00
  • EUR 3996.00
  • EUR 926.00
  • 0
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  • 2
  • Shipped within 5-7 working days.

Dihydrotestosterone (DHT) CLIA Kit

abx195018-96tests 96 tests
EUR 825.00
  • Shipped within 5-12 working days.

Dihydrotestosterone (DHT) Antibody (Biotin)

20-abx274269
  • EUR 411.00
  • EUR 230.00
  • EUR 1163.00
  • EUR 565.00
  • EUR 314.00
  • 0
  • 1
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  • Shipped within 5-7 working days.

Dihydrotestosterone (DHT) CLIA Kit

20-abx490107
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 0
  • 1
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Dihydrotestosterone (DHT) ELISA Kit

abx257148-96tests 96 tests
EUR 668.00
  • Shipped within 5-12 working days.

BSA Conjugated Dihydrotestosterone (DHT)

4-CPA443Ge11
  • EUR 413.60
  • EUR 214.00
  • EUR 1276.00
  • EUR 492.00
  • EUR 884.00
  • EUR 340.00
  • EUR 3040.00
  • 0
  • 1
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  • Uniprot ID: Inquire
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 290.4Da
  • Isoelectric Point: Inquire
Description: Recombinant Pan-species Dihydrotestosterone expressed in: Protein conjugation

OVA Conjugated Dihydrotestosterone (DHT)

4-CPA443Ge21
  • EUR 413.60
  • EUR 214.00
  • EUR 1276.00
  • EUR 492.00
  • EUR 884.00
  • EUR 340.00
  • EUR 3040.00
  • 0
  • 1
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  • Uniprot ID: Inquire
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 290.442g/mol
  • Isoelectric Point: Inquire
Description: Recombinant Pan-species Dihydrotestosterone expressed in: Protein conjugation

HEMOGLOBIN POWDER

H08-103-10kg 10 kg
EUR 2037.00

HEMOGLOBIN POWDER

H08-103-2Kg 2 Kg
EUR 447.00

HEMOGLOBIN POWDER

H08-103-500g 500 g
EUR 149.00

Zeocin, powder

GX3094-100MG 100 mg
EUR 169.00

Aluminium, powder

GX6811-1KG 1 kg
EUR 86.00

Aluminium, powder

GX6811-250G 250 g
EUR 50.00

Aluminium, powder

GX6811-500G 500 g
EUR 62.00

Talc powder

GK0095-100G 100 g
EUR 38.00

Talc powder

GK0095-1KG 1 kg
EUR 50.00

Talc powder

GK0095-2500G 2500 g
EUR 65.00

Talc powder

GK0095-500G 500 g
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GMS POWDER

G07-103-10kg 10 kg
EUR 50.00

GMS POWDER

G07-103-2Kg 2 Kg
EUR 50.00

GMS POWDER

G07-103-500g 500 g
EUR 50.00

Risperidone powder

97R-1001 10 mg
EUR 241.00
Description: Purified Risperidone powder

Diclazuril (powder)

97R-1003 100 mg
EUR 187.00
Description: Diclazuril chemical reference substance

Bromperidol (powder)

50R-R11333 50 mg
EUR 133.00
Description: Bromperidol chemical reference substance

Flubendazole (powder)

50R-R17890 50 mg
EUR 180.00
Description: Flubendazole chemical reference substance

Flunarizine (powder)

50R-R18545 50 mg
EUR 133.00
Description: Flunarizine chemical reference substance

Azaperone (powder)

50R-R1929 50 mg
EUR 133.00
Description: Azaperone chemical reference substance

Closantel (powder)

50R-R23050 50 mg
EUR 180.00
Description: Closantel chemical reference substance

Enilconazole (powder)

50R-R30617 50 mg
EUR 180.00
Description: Enilconazole chemical reference substance

Ketoconazole (powder)

50R-R41400 50 mg
EUR 133.00
Description: Ketoconazole chemical reference substance

Cisapride (powder)

50R-R51619 50 mg
EUR 133.00
Description: Cisapride chemical reference substance

Diclazuril (powder)

50R-R62370 50 mg
EUR 241.00
Description: Diclazuril chemical reference substance

Diclazuril (powder)

50R-R62646 50 mg
EUR 241.00
Description: Diclazuril chemical reference substance

Albuterol (powder)

51R-U012600 200 mg
EUR 516.00
Description: Albuterol chemical reference substance

Puromycin,Powder

CR028-001 100mg
EUR 192.00

Puromycin,Powder

CR028-005 500mg
EUR 516.00

Puromycin,Powder

CR028-101 1g
EUR 901.00

PVPP Powder

PVPP-10 10
EUR 63.00
Description: Polyvinylpyrrolidone (PVPP) used for preparation of wine samples for use with the QuantiQuikâ„¢ Histamine Quick Test Strips .

Tryptone Powder

TG217(G211) 100g
EUR 61.12
  • Product category: Culture Media/Supplements

General Dihydrotestosterone (DHT) ELISA Kit

CEA443Ge-10x96wellstestplate 10x96-wells test plate
EUR 5359.82
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of General Dihydrotestosterone (DHT) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Dihydrotestosterone (DHT) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Dihydrotestosterone (DHT) ELISA Kit

CEA443Ge-1x48wellstestplate 1x48-wells test plate
EUR 529.04
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of General Dihydrotestosterone (DHT) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Dihydrotestosterone (DHT) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Dihydrotestosterone (DHT) ELISA Kit

CEA443Ge-1x96wellstestplate 1x96-wells test plate
EUR 712.92
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of General Dihydrotestosterone (DHT) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Dihydrotestosterone (DHT) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Dihydrotestosterone (DHT) ELISA Kit

CEA443Ge-5x96wellstestplate 5x96-wells test plate
EUR 2908.14
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of General Dihydrotestosterone (DHT) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Dihydrotestosterone (DHT) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Dihydrotestosterone (DHT) ELISA Kit

4-CEA443Ge
  • EUR 5410.00
  • EUR 2859.00
  • EUR 713.00
  • 0
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  • Known also as Dihydrotestosterone elisa. Alternative names of the recognized antigen: 5α-DHT
  • 5α-Dihydrotestosterone
  • Androstanolone
  • Stanolone
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of General Dihydrotestosterone (DHT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Guinea Pig DHT ELISA Kit

EGD0008 96Tests
EUR 521.00

Chicken DHT(Dihydrotestosterone) ELISA Kit

ECH0114 96T
EUR 567.60
  • Detection range: 39.063-2500 pg/ml
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Chicken;Sensitivity: 22.5pg/ml

Dihydrotestosterone (DHT) AssayMax ELISA Kit

ED3010-1 96 Well Plate
EUR 417.00

Human Dihydrotestosterone(DHT)ELISA Kit

GA-E1082HM-48T 48T
EUR 289.00

Human Dihydrotestosterone(DHT)ELISA Kit

GA-E1082HM-96T 96T
EUR 466.00

Rat Dihydrotestosterone(DHT)ELISA Kit

GA-E0571RT-48T 48T
EUR 317.00

Rat Dihydrotestosterone(DHT)ELISA Kit

GA-E0571RT-96T 96T
EUR 496.00

Mouse Dihydrotestosterone(DHT)ELISA Kit

GA-E0700MS-48T 48T
EUR 336.00

Mouse Dihydrotestosterone(DHT)ELISA Kit

GA-E0700MS-96T 96T
EUR 534.00

Human Dihydrotestosterone,DHT ELISA Kit

201-12-1066 96 tests
EUR 440.00
  • This Dihydrotestosterone ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Dihydrotestosterone, DHT ELISA Kit

CSB-E07878h-24T 1 plate of 24 wells
EUR 165.00
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativecompetitive ELISA kit for measuring Human Dihydrotestosterone, DHT in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Dihydrotestosterone, DHT ELISA Kit

1-CSB-E07878h
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 0
  • 1
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  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativecompetitive ELISA kit for measuring Human Dihydrotestosterone, DHT in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Dihydrotestosterone, DHT ELISA Kit

CSB-E07879r-24T 1 plate of 24 wells
EUR 165.00
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativecompetitive ELISA kit for measuring Rat Dihydrotestosterone, DHT in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Dihydrotestosterone, DHT ELISA Kit

1-CSB-E07879r
  • EUR 967.00
  • EUR 5925.00
  • EUR 3134.00
  • 0
  • 1
  • 2
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativecompetitive ELISA kit for measuring Rat Dihydrotestosterone, DHT in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Dihydrotestosterone, DHT ELISA Kit

CSB-E07880m-24T 1 plate of 24 wells
EUR 165.00
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativecompetitive ELISA kit for measuring Mouse Dihydrotestosterone, DHT in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Dihydrotestosterone, DHT ELISA Kit

1-CSB-E07880m
  • EUR 946.00
  • EUR 5782.00
  • EUR 3060.00
  • 0
  • 1
  • 2
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativecompetitive ELISA kit for measuring Mouse Dihydrotestosterone, DHT in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Canine Dihydrotestosterone, DHT ELISA Kit

CSB-E07881c-24T 1 plate of 24 wells
EUR 165.00
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativecompetitive ELISA kit for measuring Canine Dihydrotestosterone, DHT in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Canine Dihydrotestosterone, DHT ELISA Kit

1-CSB-E07881c
  • EUR 967.00
  • EUR 5925.00
  • EUR 3134.00
  • 0
  • 1
  • 2
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativecompetitive ELISA kit for measuring Canine Dihydrotestosterone, DHT in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Bovine Dihydrotestosterone, DHT ELISA Kit

CELI-66100b 96 Tests
EUR 928.00

Chicken Dihydrotestosterone, DHT ELISA Kit

CELI-66100c 96 Tests
EUR 928.00

Canine Dihydrotestosterone, DHT ELISA Kit

CELI-66100d 96 Tests
EUR 928.00

General Dihydrotestosterone, DHT ELISA Kit

CELI-66100Ge 96 Tests
EUR 886.00

Human Dihydrotestosterone, DHT ELISA Kit

CELI-66100h 96 Tests
EUR 824.00

Mouse Dihydrotestosterone, DHT ELISA Kit

CELI-66100m 96 Tests
EUR 865.00

Porcine Dihydrotestosterone, DHT ELISA Kit

CELI-66100p 96 Tests
EUR 928.00

Rat Dihydrotestosterone, DHT ELISA Kit

CELI-66100r 96 Tests
EUR 886.00

Rabbit Dihydrotestosterone, DHT ELISA Kit

CELI-66100Rb 96 Tests
EUR 928.00

Rat Dihydrotestosterone,DHT ELISA Kit

CN-01938R1 96T
EUR 480.00

Rat Dihydrotestosterone,DHT ELISA Kit

CN-01938R2 48T
EUR 331.00

Mouse Dihydrotestosterone,DHT ELISA Kit

CN-02814M1 96T
EUR 441.00

Mouse Dihydrotestosterone,DHT ELISA Kit

CN-02814M2 48T
EUR 291.00

Human Dihydrotestosterone,DHT ELISA Kit

CN-03926H1 96T
EUR 448.00

Human Dihydrotestosterone,DHT ELISA Kit

CN-03926H2 48T
EUR 297.00

Canine Dihydrotestosterone,DHT ELISA Kit

CN-00948C1 96T
EUR 465.00

Canine Dihydrotestosterone,DHT ELISA Kit

CN-00948C2 48T
EUR 315.00

General DHT/ Dihydrotestosterone ELISA Kit

E0026Ge 1 Kit
EUR 717.00

ELISA kit for DHT (Dihydrotestosterone)

E-EL-0031 1 plate of 96 wells
EUR 377.00
  • Gentaur's DHT ELISA kit utilizes the Competitive-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with DHT. During the reaction, DHT in the sample or standard competes with a fixed amount of DHT on the solid phase suppo
  • Show more
Description: A competitive ELISA kit for quantitative measurement of DHT (Dihydrotestosterone) in samples from Serum, Plasma, Cell supernatant

Dihydrotestosterone (DHT) Polyclonal Antibody (General)

4-PAA443Ge01
  • EUR 228.00
  • EUR 2219.00
  • EUR 559.00
  • EUR 283.00
  • EUR 206.00
  • 0
  • 1
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  • Sequence of the immunogen: Small Molecule, DHT conjugated to OVA
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against General Dihydrotestosterone (DHT)

General Dihydrotestosterone ELISA Kit (DHT)

RK00648 96 Tests
EUR 521.00

Human Dihydrotestosterone(DHT)ELISA Kit

QY-E01470 96T
EUR 361.00

Rat Dihydrotestosterone(DHT)ELISA Kit

QY-E11081 96T
EUR 361.00

Canine Dihydrotestosterone,DHT ELISA Kit

QY-E70040 96T
EUR 426.00

Canine Dihydrotestosterone,DHT ELISA Kit

QY-E70126 96T
EUR 426.00

Mouse Dihydrotestosterone(DHT)ELISA Kit

QY-E20472 96T
EUR 361.00

Citrate Buffer Powder

AR0024 2000mL/pack
EUR 53.00

Bevacizumab Lyophilized powder

B077-5MG 5 mg
EUR 410.00

Giemsa stain, powder

GT7801-100G 100 g
EUR 134.00

Giemsa stain, powder

GT7801-10G 10 g
EUR 46.00

Giemsa stain, powder

GT7801-25G 25 g
EUR 62.00

Giemsa stain, powder

GT7801-50G 50 g
EUR 86.00

Giemsa stain, powder

GT7801-5G 5 g
EUR 42.00

Yeast extract, powder

GE4420-100G 100 g
EUR 43.00

Yeast extract, powder

GE4420-1KG 1 kg
EUR 110.00

Yeast extract, powder

GE4420-250G 250 g
EUR 54.00

Yeast extract, powder

GE4420-500G 500 g
EUR 78.00

Soya lecithin, powder

GE0442-100G 100 g
EUR 46.00

Soya lecithin, powder

GE0442-1KG 1 kg
EUR 110.00

Soya lecithin, powder

GE0442-250G 250 g
EUR 58.00

Soya lecithin, powder

GE0442-500G 500 g
EUR 78.00

Congo Red Powder

abx090680-5g 5 g
EUR 189.00
  • Shipped within 5-10 working days.

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